Investigating why treatment decisions vary for febrile infants at risk for serious infections
Official title: Using Small Area Variation Analysis to Investigate Sources of Practice Variation for Febrile Infants at Risk for Invasive Bacterial Infections
Funded at University of Rochester · NIH-11109456 · Data updated 2026-11-12
This study is looking at how doctors make different choices when treating babies with fevers who might have serious infections, so we can find ways to improve their care and make sure all infants get the right treatment without unnecessary tests or treatments.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Rochester NIH-funded |
| Lab location | 1 site (Rochester, United States) |
| Project start | May 23, 2023 |
| Project end | April 30, 2027 |
| Funding year | 2025 |
| Award (this year) | $166,946 |
| NIH project number | 5K23HD107182-03 |
| Project ID | NIH-11109456 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are febrile infants who are at risk for invasive bacterial infections.
✕Less likely to help
Patients who are not febrile or do not have risk factors for invasive bacterial infections may not benefit from this research.
What this research studies
This research focuses on understanding the differences in clinical decisions made for febrile infants who are at risk for invasive bacterial infections. By analyzing practice variations, the study aims to identify the key factors that contribute to these differences, which can lead to either under-testing or over-treatment of infants. The principal investigator, Dr. Jeffrey Yaeger, will employ new methods to investigate these sources of variation and develop interventions to improve care quality and equity for affected infants. The ultimate goal is to enhance health outcomes and reduce unnecessary healthcare costs associated with these variations.
Why it matters
Potential benefit: If successful, this research could lead to more consistent and effective treatment protocols for febrile infants, improving their health outcomes and reducing healthcare costs.
How similar studies have gone: Previous research has shown that addressing practice variation can lead to improved patient outcomes, indicating that this approach has potential for success.
Where this research is happening
-
University of Rochester
Rochester, United States Active
Researchers
- Principal investigator: Yaeger, Jeffrey Paul — University of Rochester
- Study coordinator: Yaeger, Jeffrey Paul
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.