Investigating why Latino children have a higher risk of acute lymphoblastic leukemia
Understanding the Increased Risk of Childhood Acute Lymphoblastic Leukemia in Latinos
This study is looking into why Latino children have a higher chance of developing acute lymphoblastic leukemia (ALL) by examining their genes and connections to Native American ancestry, hoping to find new ways to prevent and treat this condition.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Southern California NIH-funded |
| Lab location | 1 site (Los Angeles, UNITED STATES) |
| Project ID | NIH-11086597 on NIH RePORTER |
What this research studies
This research focuses on understanding the reasons behind the increased risk of acute lymphoblastic leukemia (ALL) in Latino children. By analyzing genetic variations and their relationship to Native American ancestry, the study aims to uncover potential risk factors that contribute to this disparity. The research involves a large-scale comparison of genetic data from over 5,400 Latino children diagnosed with ALL and 27,000 controls from various studies. The findings could lead to new insights into prevention strategies and treatment approaches for ALL.
Who could benefit from this research
Good fit: Ideal candidates for this research are Latino children under the age of 11 who have been diagnosed with acute lymphoblastic leukemia.
Not a fit: Patients who are not of Latino ethnicity or who do not have acute lymphoblastic leukemia may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved prevention and treatment strategies for acute lymphoblastic leukemia in Latino children.
How similar studies have performed: Previous research has shown success in identifying genetic risk factors for childhood cancers, making this approach promising for uncovering new insights.
Where this research is happening
Los Angeles, UNITED STATES
- University of Southern California — Los Angeles, United States (Active)
Researchers
- Principal investigator: De Smith, Adam — University of Southern California
- Study coordinator: De Smith, Adam
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.