Investigating weight gain and its health effects in people with HIV on specific treatment in Haiti.
Official title: Cardiometabolic Consequences And Pathway Of Weight Gain Associated With Dolutegravir-Based Antiretroviral Therapy In Haiti. A Collaborative Study Between GHESKIO And CCASAnet
Funded at Gheskio Center · NIH-10884392 · Data updated 2026-11-12
This study is looking at how gaining weight affects the health of people living with HIV in Haiti who are on a specific treatment, focusing on things like blood sugar, blood pressure, and cholesterol, to help find better ways to support their health.
Quick facts
| Grant type | R21 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Gheskio Center NIH-funded |
| Lab location | 1 site (Port-Au-Prince, Haiti) |
| Project start | July 10, 2023 |
| Project end | June 30, 2025 |
| Funding year | 2024 |
| Award (this year) | $168,145 |
| NIH project number | 5R21TW012644-02 |
| Project ID | NIH-10884392 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals living with HIV in Haiti who are starting or currently on a dolutegravir-based antiretroviral therapy regimen.
✕Less likely to help
Patients who are not living with HIV or those not on the specified antiretroviral therapy may not benefit from this research.
What this research studies
This research focuses on understanding the cardiometabolic risks associated with weight gain in individuals living with HIV who are receiving a specific antiretroviral therapy regimen in Haiti. The study aims to assess various health indicators such as insulin sensitivity, blood pressure, and lipid profiles to determine how weight gain impacts overall health. By analyzing these factors, the research seeks to uncover the metabolic mechanisms behind weight gain, which could inform better prevention and treatment strategies for patients. The collaborative effort involves GHESKIO, a leading HIV clinic, and aims to address a critical gap in knowledge regarding the health consequences of antiretroviral therapy in low and middle-income countries.
Why it matters
Potential benefit: If successful, this research could lead to improved health management strategies for individuals with HIV, particularly in preventing and treating weight gain and its associated health risks.
How similar studies have gone: While there is limited data on the specific consequences of weight gain in this context, similar studies in other regions have highlighted the need for targeted interventions for metabolic health in people living with HIV.
Where this research is happening
-
Gheskio Center
Port-Au-Prince, Haiti Active
Researchers
- Principal investigator: Pierre, Samuel — Gheskio Center
- Study coordinator: Pierre, Samuel
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.