Investigating ways to reduce bone fractures in patients with diabetes and other conditions
Official title: BLRD Research Career Scientist Award Application
Funded at Veterans Health Administration · NIH-11183070 · Data updated 2026-11-12
This study is looking at how diabetes, aging, and high blood pressure can lead to bone fractures and how we can help those fractures heal better, especially by understanding the role of sex hormones and certain cells in bone health.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Veterans Health Administration NIH-funded |
| Lab location | 1 site (Nashville, United States) |
| Project start | April 1, 2025 |
| Project end | September 30, 2030 |
| Funding year | 2025 |
| NIH project number | 1IK6BX007117-01 |
| Project ID | NIH-11183070 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are adults over 21 years old who have diabetes, hypertension, or other related health issues that affect bone health.
✕Less likely to help
Patients without diabetes or related conditions, or those under 21 years old, may not benefit from this research.
What this research studies
This research focuses on understanding how conditions like diabetes, aging, and hypertension contribute to bone fractures and aims to improve healing when fractures occur. The principal investigator is exploring the role of sex hormones and specific cellular mechanisms in bone health, particularly in the context of hypertension. By using advanced animal models, the research seeks to identify potential treatments that could enhance bone strength and reduce fracture risk in affected patients.
Why it matters
Potential benefit: If successful, this research could lead to new treatments that significantly lower the risk of fractures and improve healing in patients with diabetes and related conditions.
How similar studies have gone: Previous research has shown promise in understanding the relationship between hypertension and bone health, suggesting that this approach could yield valuable insights.
Where this research is happening
-
Veterans Health Administration
Nashville, United States Active
Researchers
- Principal investigator: Nyman, Jeffry Stephen — Veterans Health Administration
- Study coordinator: Nyman, Jeffry Stephen
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.