Investigating ways to improve awareness of low blood sugar in people with Type 1 Diabetes
Official title: The Biostatistics Research Center for the Impaired Awareness of Hypoglycemia Consortium
Funded at Pennsylvania State Univ Hershey Med Ctr · NIH-11073004 · Data updated 2026-11-12
This study is looking for people with Type 1 Diabetes who sometimes don't notice when their blood sugar is low, and it aims to find out how new diabetes management tools can help them feel more aware of their blood sugar levels and stay healthier.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Pennsylvania State Univ Hershey Med Ctr NIH-funded |
| Lab location | 1 site (Hershey, United States) |
| Project start | September 25, 2022 |
| Project end | December 31, 2027 |
| Funding year | 2025 |
| Award (this year) | $3,489,089 |
| NIH project number | 5U01DK135126-03 |
| Project ID | NIH-11073004 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are adults with Type 1 Diabetes who experience impaired awareness of hypoglycemia.
✕Less likely to help
Patients without Type 1 Diabetes or those who do not experience impaired awareness of hypoglycemia may not benefit from this research.
What this research studies
This research focuses on individuals with Type 1 Diabetes (T1D) who experience impaired awareness of hypoglycemia (IAH), a condition that can lead to severe health risks. The study aims to explore how modern diabetes management strategies and technology can help restore awareness of low blood sugar and improve the body's natural responses to it. By analyzing various metrics related to blood glucose levels, the research seeks to identify effective methods for enhancing patient safety and health outcomes. Participants will be involved in clinical assessments and may benefit from advanced diabetes care techniques.
Why it matters
Potential benefit: If successful, this research could significantly enhance the safety and quality of life for individuals with Type 1 Diabetes by improving their ability to recognize and respond to low blood sugar episodes.
How similar studies have gone: Previous research has shown promise in using advanced diabetes management techniques to improve awareness of hypoglycemia, suggesting that this approach may yield beneficial results.
Where this research is happening
-
Pennsylvania State Univ Hershey Med Ctr
Hershey, United States Active
Researchers
- Principal investigator: Chinchilli, Vernon M — Pennsylvania State Univ Hershey Med Ctr
- Study coordinator: Chinchilli, Vernon M
Related research
Other NIH-funded projects on the same topics.
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Technological and Educational Approaches to Restore Hypoglycemia Awareness in Type 1 Diabetes
A two-arm study in adults with type 1 diabetes tests whether high-tech glucose control plus education or targeted training can help people regain awareness of low blood sugar.
-
Techniques for restoring awareness of low blood sugar in adults with type 1 diabetes
A randomized trial compares different approaches to help adults with type 1 diabetes recognize when their blood sugar is dipping so they can act quickly.
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Treating impaired hypoglycemia awareness in type 1 diabetes with targeted education and technology
This study tests two treatment approaches to help adults with type 1 diabetes who often don’t realize their blood sugar is getting too low, using a mix of technology and education in two large groups.
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Helping people with type 1 diabetes regain awareness of dangerous lows
A UK study tests two different approaches to help adults with type 1 diabetes recognize and respond to low blood sugar by comparing a high-tech insulin system with targeted education.
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Understanding how hypoglycemia awareness changes in adults with type 1 diabetes and how automated insulin delivery and exercise might help restore it
This study will look at adults with type 1 diabetes to see how their awareness of low blood sugar evolves over time and whether automated insulin delivery and high-intensity exercise can help restore that awareness.
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Glucagon Pump Therapy for PBH in People After Bariatric Surgery
A new approach uses a patch pump and smart control to deliver glucagon during meal-related lows in adults who had bariatric surgery and developed dangerous hypoglycemia.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.