Investigating ways to delay aging and age-related diseases using genetic, drug, and diet interventions.
Hierarchy and intersection of hallmarks of aging using genetic, pharmacologic, and dietary life span extending interventions in flies and mice.
This study is looking at how changes in genes, medications, and diet might help slow down age-related diseases like Alzheimer's, using experiments on flies and mice to find new ways to improve health as we get older, which could eventually help people like you.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Brown University NIH-funded |
| Lab location | 1 site (Providence, United States) |
| Project ID | NIH-10901046 on NIH RePORTER |
What this research studies
This research aims to explore how genetic, pharmacologic, and dietary interventions can help delay the onset and progression of age-related diseases, such as Alzheimer's. By studying the interconnectedness of aging hallmarks, the researchers will identify which factors initiate aging processes and which are the effects of these processes. The study will involve experiments on flies and mice to test these interventions and their impact on health and longevity. Patients may benefit from insights gained that could lead to new therapies for age-related conditions.
Who could benefit from this research
Good fit: Ideal candidates for participation or benefit from this research are older adults or individuals at risk for age-related diseases, particularly those with a family history of Alzheimer's or similar conditions.
Not a fit: Patients who are not experiencing age-related diseases or are significantly younger may not receive direct benefits from this research.
Why it matters
Potential benefit: If successful, this research could lead to new treatments that significantly improve health and longevity for aging individuals.
How similar studies have performed: Other research has shown promise in using genetic and dietary interventions to influence aging, suggesting that this approach could yield significant insights.
Where this research is happening
Providence, United States
- Brown University — Providence, United States (Active)
Researchers
- Principal investigator: Helfand, Stephen L — Brown University
- Study coordinator: Helfand, Stephen L
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.