Investigating vaccines for Nipah and Hendra viruses
Project 1 - Profectus Biosciences, Inc.
This study is working on a new vaccine to help protect people from the Nipah and Hendra viruses, which are serious illnesses with no current treatments, and it's based on a successful horse vaccine used in Australia.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Henry M. Jackson Fdn for the Adv Mil/med NIH-funded |
| Lab location | 1 site (Bethesda, United States) |
| Project ID | NIH-10581498 on NIH RePORTER |
What this research studies
This research focuses on developing vaccines for Nipah virus (NiV) and Hendra virus (HeV), which are highly dangerous viruses with no approved treatments. The project aims to evaluate the immunogenicity and effectiveness of a proposed human subunit vaccine, leveraging existing knowledge from a horse vaccine that has been successfully used in Australia. By conducting clinical evaluations and testing, the research seeks to provide a viable prophylactic option to protect against these biothreat agents, especially in endemic regions. The approach includes preclinical studies and monitoring the transmission processes of these viruses.
Who could benefit from this research
Good fit: Ideal candidates for participation would include individuals living in endemic areas or those at high risk of exposure to these viruses.
Not a fit: Patients who are not at risk of exposure to Nipah or Hendra viruses may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to the development of effective vaccines that protect against severe diseases caused by Nipah and Hendra viruses.
How similar studies have performed: Previous research on vaccines for similar biothreat viruses has shown promise, indicating potential for success in this area.
Where this research is happening
Bethesda, United States
- Henry M. Jackson Fdn for the Adv Mil/med — Bethesda, United States (Active)
Researchers
- Principal investigator: Eldridge, John Hayward — Henry M. Jackson Fdn for the Adv Mil/med
- Study coordinator: Eldridge, John Hayward
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.