Investigating Type 2 Diabetes in Navajo Youth

Understanding the Pathophysiology of Type 2 Diabetes in Navajo Youth

NIH-funded research University of Colorado Denver · NIH-11051245

This study is looking at how Type 2 diabetes starts in Navajo kids, especially during puberty, to find out what causes it and how we can help prevent it in young people who might be at risk.

Quick facts

Grant typeU01 cooperative agreement
Study typeNIH-funded research
Funding institutionUniversity of Colorado Denver NIH-funded
Lab location1 site (Aurora, UNITED STATES)
Project IDNIH-11051245 on NIH RePORTER

What this research studies

This research focuses on understanding how Type 2 diabetes develops in Navajo youth, particularly during puberty when significant changes in insulin sensitivity occur. The study aims to identify the biological markers and patterns that lead to youth-onset diabetes, which is becoming increasingly common among American Indian populations. By examining these factors over time, the research seeks to uncover critical insights that could inform targeted prevention strategies for at-risk youth. Participants may undergo assessments related to their body mass index, insulin levels, and other health metrics.

Who could benefit from this research

Good fit: Ideal candidates for this research are Navajo youth under 21 years old who are at risk for developing Type 2 diabetes.

Not a fit: Patients who are not part of the Navajo community or those over 21 years old may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved prevention strategies for Type 2 diabetes in young people, particularly in the Navajo community.

How similar studies have performed: Previous research has indicated that understanding the biological mechanisms of diabetes in youth can lead to effective prevention strategies, suggesting that this approach has potential for success.

Where this research is happening

Aurora, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions adult onset diabetesAdult-Onset Diabetes Mellitus
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.