Investigating tumor-derived microvesicles and their role in cancer
New approaches to study tumor microvesicles
['FUNDING_R03'] · UNIVERSITY OF NOTRE DAME · NIH-10681484
This study is looking at tiny particles released by tumor cells to see how they help tumors grow and affect the immune system, with the hope of finding new ways to treat cancer and improve patient care.
Quick facts
| Phase | ['FUNDING_R03'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF NOTRE DAME (nih funded) |
| Locations | 1 site (NOTRE DAME, UNITED STATES) |
| Trial ID | NIH-10681484 on ClinicalTrials.gov |
What this research studies
This research focuses on tumor-derived microvesicles (TMVs), which are small vesicles released by tumor cells that play a significant role in how tumors communicate and interact with their environment. The study aims to understand how these vesicles are formed and how they influence cancer progression, immune responses, and blood vessel formation. By identifying the molecules and pathways involved in TMV biogenesis, the research seeks to uncover new therapeutic strategies and potential diagnostic tools for cancer treatment. Patients may benefit from insights gained about TMVs that could lead to improved cancer therapies.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with various types of cancers, particularly those with advanced or metastatic disease.
Not a fit: Patients with non-malignant conditions or early-stage cancers may not receive direct benefits from this research.
Why it matters
Potential benefit: If successful, this research could lead to new treatments and diagnostic methods for cancer patients.
How similar studies have performed: Previous research has shown promise in understanding extracellular vesicles in cancer, but the specific focus on tumor-derived microvesicles is relatively novel.
Where this research is happening
NOTRE DAME, UNITED STATES
- UNIVERSITY OF NOTRE DAME — NOTRE DAME, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: D'SOUZA-SCHOREY, CRISLYN — UNIVERSITY OF NOTRE DAME
- Study coordinator: D'SOUZA-SCHOREY, CRISLYN
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Cancers, neoplasm/cancer