Investigating tumor biology differences in multiple myeloma among individuals of African ancestry
Differences in Tumor Biology of Multiple Myeloma in Association with African Ancestry
This study is looking at how multiple myeloma affects Black/African American people differently than European Americans, aiming to find out why there are differences in health outcomes and what factors might be involved, so we can improve care for everyone.
Quick facts
| Grant type | R37 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Mayo Clinic Rochester NIH-funded |
| Lab location | 1 site (Rochester, United States) |
| Project ID | NIH-10931365 on NIH RePORTER |
What this research studies
This research focuses on understanding how multiple myeloma, a common blood cancer, affects Black/African American individuals differently compared to European Americans. It aims to explore the genetic variations of tumors and their microenvironments in newly diagnosed patients, with a particular emphasis on those of African ancestry. By analyzing these differences, the study seeks to uncover the reasons behind health disparities in incidence and outcomes for African American patients. The research will involve large-scale comparisons to identify biological, environmental, and healthcare access factors that contribute to these disparities.
Who could benefit from this research
Good fit: Ideal candidates for this research are newly diagnosed African American individuals with multiple myeloma.
Not a fit: Patients of non-African ancestry or those with other types of cancers may not receive direct benefits from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved treatment strategies and outcomes for African American patients with multiple myeloma.
How similar studies have performed: Previous research has highlighted significant disparities in cancer outcomes based on ancestry, suggesting that this approach could yield valuable insights.
Where this research is happening
Rochester, United States
- Mayo Clinic Rochester — Rochester, United States (Active)
Researchers
- Principal investigator: Baughn, Linda B — Mayo Clinic Rochester
- Study coordinator: Baughn, Linda B
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.