Investigating tuberculosis diagnosis and treatment in Brazil

Regional Prospective Observational Research in Tuberculosis (RePORT) – Brazil Network

NIH-funded research Vanderbilt University Medical Center · NIH-11013296

This study is looking at tuberculosis (TB) in Brazil to find better ways to diagnose, treat, and prevent the disease by gathering information from TB patients and those close to them, so we can improve health strategies for everyone affected.

Quick facts

Grant typeU01 cooperative agreement
Study typeNIH-funded research
Funding institutionVanderbilt University Medical Center NIH-funded
Lab location1 site (Nashville, United States)
Project IDNIH-11013296 on NIH RePORTER

What this research studies

This research focuses on understanding tuberculosis (TB) in Brazil, which has one of the highest burdens of the disease globally. It aims to improve TB diagnosis, treatment, and prevention by analyzing clinical data and biological samples from TB patients and their close contacts. The study will build on previous findings to explore factors influencing TB outcomes, including drug resistance and co-infections like HIV. Patients will be enrolled to provide new insights into TB epidemiology and enhance public health strategies.

Who could benefit from this research

Good fit: Ideal candidates for this research include individuals diagnosed with tuberculosis and their close contacts in Brazil.

Not a fit: Patients with no history of tuberculosis or those living outside of Brazil may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved TB treatment and prevention strategies, ultimately reducing the incidence and mortality of the disease.

How similar studies have performed: Previous research in similar settings has shown promise in improving TB outcomes, indicating that this approach could be effective.

Where this research is happening

Nashville, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Acquired Immune Deficiency SyndromeAcquired Immune Deficiency Syndrome VirusAcquired Immunodeficiency SyndromeAcquired Immunodeficiency Syndrome Virus
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.