Investigating tuberculosis diagnosis and treatment in Brazil
Official title: Regional Prospective Observational Research in Tuberculosis (RePORT) – Brazil Network
Funded at Vanderbilt University Medical Center · NIH-11013296 · Data updated 2026-11-12
This study is looking at tuberculosis (TB) in Brazil to find better ways to diagnose, treat, and prevent the disease by gathering information from TB patients and those close to them, so we can improve health strategies for everyone affected.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Vanderbilt University Medical Center NIH-funded |
| Lab location | 1 site (Nashville, United States) |
| Project start | January 2, 2023 |
| Project end | December 31, 2027 |
| Funding year | 2025 |
| Award (this year) | $1,000,000 |
| NIH project number | 5U01AI172064-03 |
| Project ID | NIH-11013296 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include individuals diagnosed with tuberculosis and their close contacts in Brazil.
✕Less likely to help
Patients with no history of tuberculosis or those living outside of Brazil may not benefit from this research.
What this research studies
This research focuses on understanding tuberculosis (TB) in Brazil, which has one of the highest burdens of the disease globally. It aims to improve TB diagnosis, treatment, and prevention by analyzing clinical data and biological samples from TB patients and their close contacts. The study will build on previous findings to explore factors influencing TB outcomes, including drug resistance and co-infections like HIV. Patients will be enrolled to provide new insights into TB epidemiology and enhance public health strategies.
Why it matters
Potential benefit: If successful, this research could lead to improved TB treatment and prevention strategies, ultimately reducing the incidence and mortality of the disease.
How similar studies have gone: Previous research in similar settings has shown promise in improving TB outcomes, indicating that this approach could be effective.
Where this research is happening
-
Vanderbilt University Medical Center
Nashville, United States Active
Researchers
- Principal investigator: Sterling, Timothy R — Vanderbilt University Medical Center
- Study coordinator: Sterling, Timothy R
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.