Investigating true treatment-resistant hypertension in African Americans
Determining true versus apparent treatment-resistant hypertension among African Americans in the Jackson Heart Study
This study is looking at high blood pressure that doesn't respond to treatment in African Americans to find out if it's really treatment-resistant or if there are other reasons, like incorrect blood pressure readings or not taking medications as prescribed, and it involves checking in with 400 people who have this issue and 200 who do respond to treatment.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Alabama at Birmingham NIH-funded |
| Lab location | 1 site (Birmingham, United States) |
| Project ID | NIH-10914868 on NIH RePORTER |
What this research studies
This research focuses on understanding treatment-resistant hypertension among African Americans, a group that experiences higher rates of hypertension and cardiovascular disease. The study aims to differentiate between true treatment-resistant hypertension and apparent treatment-resistant hypertension, which may be due to factors like inaccurate blood pressure measurements or poor medication adherence. By analyzing data from the Jackson Heart Study, the researchers will evaluate 400 participants with treatment-resistant hypertension and 200 who respond to treatment, conducting thorough clinical assessments to identify underlying causes. This approach will help clarify the prevalence and characteristics of true treatment-resistant hypertension in this population.
Who could benefit from this research
Good fit: Ideal candidates for this research are African American adults who have been diagnosed with treatment-resistant hypertension.
Not a fit: Patients who do not have hypertension or those outside the African American demographic may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better diagnosis and treatment strategies for African Americans suffering from hypertension.
How similar studies have performed: Previous research has shown success in similar approaches to understanding hypertension, particularly in diverse populations, but this specific focus on African Americans and treatment-resistant hypertension is relatively novel.
Where this research is happening
Birmingham, United States
- University of Alabama at Birmingham — Birmingham, United States (Active)
Researchers
- Principal investigator: Gabriel, Kelley Pettee — University of Alabama at Birmingham
- Study coordinator: Gabriel, Kelley Pettee
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.