Investigating treatments for loss-of-control eating after weight loss surgery
Using a SMART Design to Examine Pharmacological and Behavioral Treatments to Treat Loss-of-Control Eating and Improve Weight Outcomes after Metabolic and Bariatric Surgery
This study is looking for people who have had weight loss surgery and are having trouble with overeating, to see if different types of treatments can help them manage their eating better and improve their health over 16 weeks.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Yale University NIH-funded |
| Lab location | 1 site (New Haven, United States) |
| Project ID | NIH-10690563 on NIH RePORTER |
What this research studies
This research focuses on patients who have undergone metabolic and bariatric surgery (MBS) and are experiencing loss-of-control eating, a condition that can hinder weight loss success. The study will involve a randomized controlled trial where participants will be assigned to different treatment groups to evaluate the effectiveness of both behavioral and pharmacological interventions over 16 weeks. By examining these treatments, the research aims to identify effective strategies to improve weight outcomes and overall health for patients struggling with this issue after surgery.
Who could benefit from this research
Good fit: Ideal candidates for this research are adults over 21 years old who have undergone metabolic and bariatric surgery and are experiencing loss-of-control eating.
Not a fit: Patients who have not had metabolic and bariatric surgery or do not experience loss-of-control eating may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved weight management and health outcomes for patients after metabolic and bariatric surgery.
How similar studies have performed: While there has been limited research on pharmacological treatments for loss-of-control eating post-surgery, similar behavioral interventions have shown promise in other obesity-related studies.
Where this research is happening
New Haven, United States
- Yale University — New Haven, United States (Active)
Researchers
- Principal investigator: Grilo, Carlos M — Yale University
- Study coordinator: Grilo, Carlos M
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.