NIH-funded research U01 cooperative agreement

Investigating treatments for food allergies, particularly peanut allergies.

Official title: Consortium for food allergy research clinical center CoFar

Funded at Boston Children's Hospital · NIH-11053640 · Data updated 2026-11-12

This study is looking at how a special treatment that changes the bacteria in your gut might help teenagers with peanut allergies feel better and have fewer allergic reactions.

More Allergy research and trials

Quick facts

Grant typeU01 cooperative agreement
Study typeNIH-funded research
Funding institutionBoston Children's Hospital
NIH-funded
Lab location1 site (Boston, United States)
Project startMarch 11, 2024
Project endFebruary 28, 2031
Funding year2025
Award (this year)$380,000
NIH project number5U01AI181964-02
Project IDNIH-11053640 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates include individuals aged 0-11 years and 21+ years who have a diagnosed peanut allergy.

Less likely to help

Patients with food allergies other than peanut allergies may not receive direct benefits from this research.

What this research studies

This research focuses on food allergies, especially peanut allergies, by bringing together experienced clinical and laboratory investigators. They will conduct clinical trials and observational studies to explore the safety and efficacy of microbiota transplantation therapy in teens with peanut allergies. The study aims to understand how manipulating the microbiome can impact allergic responses and improve treatment outcomes. Participants from diverse backgrounds and age groups will be recruited to ensure comprehensive data collection.

Why it matters

Potential benefit: If successful, this research could lead to new, effective treatments for individuals suffering from food allergies, particularly peanut allergies.

How similar studies have gone: Previous research has shown promising results with microbiota manipulation in adults with food allergies, indicating potential for success in this study.

Where this research is happening

  • Boston Children's Hospital
    Boston, United States
    Active

Researchers

  • Principal investigator: Rachid, Rima — Boston Children's Hospital
  • Study coordinator: Rachid, Rima

Related research

Other NIH-funded projects on the same topics.

  • New Horizons in preventing and treating food allergy

    A Johns Hopkins-led effort aims to advance how we prevent and treat food allergies across all ages by coordinating high-quality studies and developing better therapies.

    NIH research Johns Hopkins University · Baltimore, United States · NIH-11600582

  • New Horizons in Food Allergy Prevention and Treatment

    A large, multi-site program at Johns Hopkins aims to advance prevention and treatment of food allergies across all ages.

    NIH research Johns Hopkins University · Baltimore, United States · NIH-11580809

  • Food allergy outcomes by race/ethnicity from infancy through adolescence

    This study follows children with food allergies over time to understand how race and ethnicity relate to allergy management, outcomes, and quality of life.

    NIH research Northwestern University · Chicago, United States · NIH-11579222

  • Gut-brain links in food allergy responses

    A research grant is exploring how signals between the gut and brain drive dangerous reactions to foods, with the goal of helping people with food allergies.

    NIH research Yale University · New Haven, United States · NIH-11551492

  • Targeting gut microbes to restore food-tolerance in adults

    Aims to understand how gut bacteria and the lining of the gut interact to keep people with food allergies tolerant to what they eat.

    NIH research Boston Children's Hospital · Boston, United States · NIH-11551491

  • Environment and early-life exposures shaping food allergy in children

    This grant looks at how a child’s first year and their home environment may influence whether they develop food allergies, focusing on indoor exposures and microbes.

    NIH research Univ of North Carolina Chapel Hill · Chapel Hill, United States · NIH-11450430

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.