Investigating treatments for COVID-19 in outpatient settings
ACTIV-6
This study is looking for people with COVID-19 to try out some existing medications that might help them feel better without needing to go to the hospital, and it involves several well-known medical centers working together to make sure the treatments are safe and effective.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Duke University NIH-funded |
| Lab location | 1 site (Durham, United States) |
| Project ID | NIH-10442110 on NIH RePORTER |
What this research studies
This research aims to create a platform for testing various repurposed medications that have shown promise in treating COVID-19. By utilizing a master clinical trial protocol, the study will evaluate the effectiveness and safety of these treatments in outpatient settings, where patients can receive care without hospitalization. The collaboration involves multiple institutions, including Duke University and Vanderbilt University Medical Center, to ensure a comprehensive approach to addressing the ongoing challenges posed by COVID-19. Patients will be monitored for outcomes related to their COVID-19 infection and overall health.
Who could benefit from this research
Good fit: Ideal candidates for participation include adults experiencing COVID-19 symptoms who are seeking outpatient treatment options.
Not a fit: Patients who are currently hospitalized for severe COVID-19 or those who have already received definitive treatment may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could provide effective outpatient treatment options for COVID-19, potentially reducing hospitalizations and improving patient outcomes.
How similar studies have performed: Previous research has shown success in repurposing existing medications for COVID-19 treatment, indicating a promising avenue for this approach.
Where this research is happening
Durham, United States
- Duke University — Durham, United States (Active)
Researchers
- Principal investigator: Benjamin, Daniel K. — Duke University
- Study coordinator: Benjamin, Daniel K.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.