Investigating treatments for age-related neurodegenerative diseases in Veterans
Official title: BLR&D MERIT REVIEW RESEARCH CAREER SCIENTIST AWARD APPLICATION
Funded at VA San Diego Healthcare System · NIH-11101253 · Data updated 2026-11-12
This study is looking for new ways to help Veterans with age-related brain diseases like Alzheimer's and ALS by using special treatments that could improve their thinking and movement skills.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | VA San Diego Healthcare System NIH-funded |
| Lab location | 1 site (San Diego, United States) |
| Project start | April 1, 2023 |
| Project end | March 31, 2028 |
| Funding year | 2025 |
| NIH project number | 5IK6BX006318-03 |
| Project ID | NIH-11101253 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include Veterans experiencing age-related neurodegenerative diseases or those at risk due to their medical history.
✕Less likely to help
Patients with neurodegenerative diseases unrelated to aging or those who do not have a military background may not benefit from this research.
What this research studies
This research focuses on understanding and developing interventions for age-related neurodegenerative diseases, such as Alzheimer's disease and amyotrophic lateral sclerosis, particularly in the Veteran population. The approach involves targeting molecular mechanisms through genetic and pharmacologic methods to enhance neuronal and synaptic function, which may improve cognitive and motor abilities. The study aims to address the increasing prevalence of these conditions among Veterans, especially those with complex injuries from recent conflicts. By exploring innovative delivery methods, such as adeno-associated viral vectors, the research seeks to provide new therapeutic options for affected individuals.
Why it matters
Potential benefit: If successful, this research could lead to improved treatments for Veterans suffering from debilitating neurodegenerative diseases, enhancing their quality of life.
How similar studies have gone: Previous research has shown promise in using genetic and pharmacologic interventions to improve outcomes in neurodegenerative diseases, indicating a potential for success in this approach.
Where this research is happening
-
VA San Diego Healthcare System
San Diego, United States Active
Researchers
- Principal investigator: Head, Brian P — VA San Diego Healthcare System
- Study coordinator: Head, Brian P
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.