Investigating treatment outcomes for patients with critical limb ischemia and end-stage renal disease

Outcomes and perspectives on treatment for critical limb ischemia in patients with end-stage renal disease

NIH-funded research University of Florida · NIH-10897869

This study is looking at the best treatment options for people with critical limb ischemia who also have severe kidney disease, to help doctors and patients make better choices about care and improve health outcomes.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionUniversity of Florida NIH-funded
Lab location1 site (Gainesville, United States)
Project IDNIH-10897869 on NIH RePORTER

What this research studies

This research focuses on understanding the treatment options and outcomes for patients suffering from critical limb ischemia (CLI) who also have end-stage renal disease (ESRD). It examines various treatment methods, including catheter-based procedures, surgery, and symptom management, to determine their effectiveness and impact on patient mortality and amputation rates. The study aims to gather real-world evidence to guide treatment decisions and improve shared decision-making between patients and healthcare providers. By analyzing patient outcomes and factors influencing treatment choices, the research seeks to develop clinical care guidelines tailored for this vulnerable population.

Who could benefit from this research

Good fit: Ideal candidates for this research are patients diagnosed with both critical limb ischemia and end-stage renal disease.

Not a fit: Patients who do not have critical limb ischemia or end-stage renal disease may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved treatment strategies and better outcomes for patients with critical limb ischemia and end-stage renal disease.

How similar studies have performed: While there is limited existing literature on this specific patient population, similar studies have shown the importance of real-world evidence in improving treatment outcomes for complex conditions.

Where this research is happening

Gainesville, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-10 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.