Investigating treatment options for urgency incontinence in older women
Cognitive, urinary, and functional trajectories of older women using pharmacologic treatment strategies for urgency incontinence
This study is looking at how two different types of medications can help older women with urgency incontinence, focusing on how they affect both bladder control and thinking skills over time.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California, San Francisco NIH-funded |
| Lab location | 1 site (San Francisco, United States) |
| Project ID | NIH-11013369 on NIH RePORTER |
What this research studies
This research focuses on older women suffering from urgency incontinence, a condition that can lead to significant emotional and physical challenges. It aims to compare the effects of traditional anticholinergic medications with a newer non-anticholinergic option, mirabegron, on cognitive function and overall health. By conducting a prospective trial, the study seeks to provide clearer insights into how these treatments impact not only bladder control but also cognitive health and daily functioning. Patients will be monitored over time to assess changes in their cognitive abilities and urinary symptoms.
Who could benefit from this research
Good fit: Ideal candidates for this research are women over the age of 60 who experience urgency incontinence.
Not a fit: Patients who do not have urgency incontinence or are under the age of 60 may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to safer and more effective treatment options for urgency incontinence that do not compromise cognitive health.
How similar studies have performed: While there have been observational studies on anticholinergic medications and cognitive decline, this research represents a novel prospective approach to directly assess the impact of different treatment strategies.
Where this research is happening
San Francisco, United States
- University of California, San Francisco — San Francisco, United States (Active)
Researchers
- Principal investigator: Huang, Alison — University of California, San Francisco
- Study coordinator: Huang, Alison
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.