Investigating therapies for Down Syndrome Regression Disorder
Mechanistic investigation of therapies for Down Syndrome Regression Disorder
This study is looking into Down Syndrome Regression Disorder, which can cause serious challenges like losing the ability to communicate and difficulties with daily activities, and it aims to find out what causes these issues and how different treatments, like medications and immunotherapy, can help improve the lives of those affected.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Colorado Denver NIH-funded |
| Lab location | 1 site (Aurora, UNITED STATES) |
| Project ID | NIH-11145996 on NIH RePORTER |
What this research studies
This research focuses on understanding Down Syndrome Regression Disorder (DSRD), a condition affecting individuals with Down syndrome that leads to severe symptoms such as loss of communication, aggression, and inability to perform daily activities. The study aims to explore the underlying causes of DSRD and evaluate the effectiveness of various therapeutic approaches, including psychiatric medications and immunotherapy. By conducting a comprehensive clinical program, the research seeks to provide insights into the safety and efficacy of these treatments, potentially improving care for affected individuals.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with Down syndrome who are experiencing symptoms of regression, such as loss of communication or aggressive behavior.
Not a fit: Patients with Down syndrome who do not exhibit symptoms of regression or related neurological conditions may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective treatments for individuals with Down Syndrome Regression Disorder, improving their quality of life.
How similar studies have performed: While there is ongoing research into therapies for Down syndrome and related conditions, the specific investigation of Down Syndrome Regression Disorder and its treatments is relatively novel.
Where this research is happening
Aurora, UNITED STATES
- University of Colorado Denver — Aurora, United States (Active)
Researchers
- Principal investigator: Espinosa, Joaquin M. — University of Colorado Denver
- Study coordinator: Espinosa, Joaquin M.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.