Investigating the use of surgical mesh in breast reconstruction after mastectomy

Randomized Feasibility Trial for Mesh in Pre-Pectoral Reconstruction

NIH-funded research University of California Los Angeles · NIH-10553174

This study is looking at how using surgical mesh during breast reconstruction after a mastectomy affects recovery and satisfaction, and it's for women who are considering this procedure.

Quick facts

Grant typeR21 grant
Study typeNIH-funded research
Funding institutionUniversity of California Los Angeles NIH-funded
Lab location1 site (Los Angeles, United States)
Project IDNIH-10553174 on NIH RePORTER

What this research studies

This research explores the feasibility of using surgical mesh devices in pre-pectoral breast reconstruction, which is a procedure performed after mastectomy to restore the breast's appearance. The study aims to compare the outcomes of patients receiving implants with and without the use of mesh, focusing on both physical and psychological recovery. By conducting a randomized trial, the researchers hope to gather robust data on the risks and benefits associated with this approach, which has not been thoroughly evaluated in prior studies. Patients participating in this trial will be closely monitored to assess their satisfaction and overall health outcomes following the procedure.

Who could benefit from this research

Good fit: Ideal candidates for this research are women who are undergoing mastectomy due to breast cancer and are considering breast reconstruction.

Not a fit: Patients who have already undergone breast reconstruction or those not seeking reconstruction after mastectomy may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved breast reconstruction techniques that enhance patient satisfaction and reduce complications.

How similar studies have performed: While there have been small studies on submuscular reconstructions, this approach using mesh in pre-pectoral reconstruction is relatively novel and has not been extensively tested in a randomized trial format.

Where this research is happening

Los Angeles, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Breast Cancer
Last reviewed 2026-06-10 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.