Investigating the use of cannabis and opioids for managing chronic pain
Official title: Exploring Reactivity Among Patients with Chronic Pain Using Cannabis and Opioids: Mixed-Method Evidence of Promising Intervention Strategies
Funded at Johns Hopkins University · NIH-10996922 · Data updated 2026-11-12
This study is looking at how using cannabis along with opioids might help people with chronic pain find better relief while staying safe, and it’s for anyone who struggles with pain and wants to explore different treatment options.
Quick facts
| Grant type | Fellowship grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Johns Hopkins University NIH-funded |
| Lab location | 1 site (Baltimore, United States) |
| Project start | September 15, 2024 |
| Project end | September 14, 2026 |
| Funding year | 2024 |
| Award (this year) | $73,828 |
| NIH project number | 1F32DA061600-01 |
| Project ID | NIH-10996922 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals experiencing chronic pain who are currently using or considering using cannabis or opioids for pain relief.
✕Less likely to help
Patients who do not have chronic pain or those who are not interested in using cannabis or opioids for pain management may not benefit from this research.
What this research studies
This research explores how cannabis and opioids can be used together to manage chronic pain, a condition affecting over 100 million people in the U.S. The study aims to understand the effectiveness of these treatments and their potential risks, particularly in light of the opioid epidemic. By examining patient experiences and outcomes, the research seeks to identify safer alternatives to prescription opioids for pain relief. Participants may provide valuable insights into their pain management strategies and the impact of cannabis use.
Why it matters
Potential benefit: If successful, this research could lead to safer and more effective pain management options for patients suffering from chronic pain.
How similar studies have gone: Previous research has shown promising results in using cannabinoids for pain management, indicating potential for success in this mixed-method approach.
Where this research is happening
-
Johns Hopkins University
Baltimore, United States Active
Researchers
- Principal investigator: Stone, Bryant Michael — Johns Hopkins University
- Study coordinator: Stone, Bryant Michael
Related research
Other NIH-funded projects on the same topics.
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Investigating how cannabis and opioid policies affect chronic pain and overdose rates
This study looks at how legalizing cannabis and changing prescription rules for opioids affect how doctors manage chronic pain and the risk of overdose, helping patients find safer ways to handle their pain.
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A study in rodents and people tests whether non-invasive brain stimulation of the motor cortex can reduce chronic pain and how best to target it.
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A large NIH-funded project will map and study the human trigeminal neurons involved in migraines to understand what changes in these cells during headache conditions.
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Understanding human pain neurons to improve migraine care
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.