Investigating the use of bilevel positive airway pressure for treating severe asthma in children.
Understanding the role of bilevel positive airway pressure (BPAP) in pediatric acute asthma exacerbations: A prospective, randomized, double blind, controlled trial.
This study is looking at whether a special breathing machine called BPAP can help kids with severe asthma attacks breathe better and recover faster compared to regular treatments they usually get in the emergency room.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Colorado Denver NIH-funded |
| Lab location | 1 site (Aurora, UNITED STATES) |
| Project ID | NIH-10918225 on NIH RePORTER |
What this research studies
This research focuses on the effectiveness and safety of bilevel positive airway pressure (BPAP) in children experiencing acute asthma exacerbations. It involves a prospective, randomized, double-blind, controlled trial where pediatric patients presenting to the emergency department will receive either BPAP or standard treatment. The aim is to see if BPAP can improve airway function and reduce the need for additional medication, ultimately enhancing patient recovery. By gathering data on its impact, the study hopes to establish BPAP as a viable treatment option for severe asthma in children.
Who could benefit from this research
Good fit: Ideal candidates for this research are children aged 0 to 17 years who are experiencing moderate to severe asthma exacerbations and have not responded adequately to first-line therapies.
Not a fit: Patients with mild asthma or those who do not present with acute exacerbations may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could provide a new, effective treatment option for children suffering from severe asthma attacks, potentially reducing hospitalizations and improving recovery times.
How similar studies have performed: While BPAP is commonly used in adult populations, this research is novel in its focus on pediatric patients and aims to fill a gap in existing clinical guidelines.
Where this research is happening
Aurora, UNITED STATES
- University of Colorado Denver — Aurora, United States (Active)
Researchers
- Principal investigator: Wilson, Patrick Thomas — University of Colorado Denver
- Study coordinator: Wilson, Patrick Thomas
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.