Investigating the thalamus's role in schizophrenia and cognitive function

Research and mentoring on cognitive neuroscience and high-field MRI of the thalamus in schizophrenia

NIH-funded research Vanderbilt University Medical Center · NIH-10908599

This study is looking at how a part of the brain called the thalamus works in people with schizophrenia, to better understand its role in thinking and learning, and to help improve treatments for cognitive challenges related to the condition.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionVanderbilt University Medical Center NIH-funded
Lab location1 site (Nashville, United States)
Project IDNIH-10908599 on NIH RePORTER

What this research studies

This research focuses on understanding how the thalamus, a key brain structure, is connected and functions in individuals with schizophrenia. By using advanced neuroimaging techniques, the study aims to explore the thalamic connectivity and its impact on cognitive abilities in psychotic disorders. The principal investigator will also mentor trainees in this field, enhancing the research community's knowledge and skills related to cognitive neuroscience and psychosis. The goal is to bridge the gap between basic neuroscience findings and their application to treatment strategies for cognitive impairments.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals diagnosed with schizophrenia who experience cognitive impairments.

Not a fit: Patients without a diagnosis of schizophrenia or those who do not experience cognitive disturbances may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to new insights and potential treatment targets for cognitive impairments associated with schizophrenia.

How similar studies have performed: Previous research has shown promising results in understanding thalamic connectivity in schizophrenia, suggesting that this approach could yield valuable insights.

Where this research is happening

Nashville, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.