Investigating the spread of isoniazid-resistant tuberculosis in Haiti
Official title: Sentinel populations and transmission hotspots of isoniazid-resistant tuberculosis
Funded at Weill Medical Coll of Cornell Univ · NIH-10887506 · Data updated 2026-11-12
This study is looking at how isoniazid-resistant tuberculosis spreads among teenagers in Haiti, using special tools to find out where it’s happening, so we can come up with better ways to help keep everyone healthy.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Weill Medical Coll of Cornell Univ NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project start | July 13, 2023 |
| Project end | June 30, 2028 |
| Funding year | 2024 |
| Award (this year) | $195,480 |
| NIH project number | 5K23AI175686-02 |
| Project ID | NIH-10887506 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include adolescents and young adults in Haiti who are at risk of or affected by isoniazid-resistant tuberculosis.
✕Less likely to help
Patients who do not reside in Haiti or who are not part of the adolescent population may not benefit from this research.
What this research studies
This research focuses on understanding the transmission patterns of isoniazid-resistant tuberculosis (INHr-TB) in Haiti, particularly among adolescents. The project utilizes advanced techniques such as whole genome sequencing and geographic information systems (GIS) to map and analyze the spread of this drug-resistant form of TB. By identifying hotspots of transmission outside of households, the research aims to inform better public health strategies and interventions. The principal investigator, Dr. Kathleen Walsh, has extensive experience in treating drug-resistant TB and has trained local healthcare teams in research methodologies.
Why it matters
Potential benefit: If successful, this research could lead to improved strategies for controlling and preventing the spread of drug-resistant tuberculosis, ultimately saving lives.
How similar studies have gone: Previous research has shown success in using molecular epidemiology and GIS mapping to track and control infectious diseases, suggesting that this approach could be effective for tuberculosis as well.
Where this research is happening
-
Weill Medical Coll of Cornell Univ
New York, United States Active
Researchers
- Principal investigator: Walsh, Kathleen F — Weill Medical Coll of Cornell Univ
- Study coordinator: Walsh, Kathleen F
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.