Investigating the sources and risk factors of urinary tract infections in Ecuador
Zoonotic Uropathogenic Escherichia coli in Northwest Ecuador: Incidence and Risk Factors
This study is looking into how certain germs that cause urinary tract infections are spread in communities in northwestern Ecuador, especially by examining the connections between people, animals, and the environment, to help find ways to reduce these infections.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Michigan at Ann Arbor NIH-funded |
| Lab location | 1 site (Ann Arbor, United States) |
| Project ID | NIH-10890039 on NIH RePORTER |
What this research studies
This research focuses on understanding how Uropathogenic Escherichia coli (UPEC) strains, which are responsible for most urinary tract infections (UTIs), are transmitted in low- and middle-income countries, particularly in northwestern Ecuador. By using advanced genomic techniques, the study aims to identify the environmental sources of UPEC, including those from food-animal products, and assess the risk factors associated with their transmission in marginalized communities. The research will involve collecting data on human-animal interactions and analyzing the genetic makeup of UPEC strains to better understand their epidemiology. This comprehensive approach seeks to fill the knowledge gap regarding UPEC transmission in these regions.
Who could benefit from this research
Good fit: Ideal candidates for participation or benefit from this research include individuals living in marginalized communities in northwestern Ecuador who are at risk for urinary tract infections.
Not a fit: Patients living outside of the study area or those not at risk for urinary tract infections may not receive any benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved prevention strategies for urinary tract infections, particularly in vulnerable populations.
How similar studies have performed: Previous research has shown success in understanding UPEC transmission in other contexts, but this specific approach in low- and middle-income countries is relatively novel.
Where this research is happening
Ann Arbor, United States
- University of Michigan at Ann Arbor — Ann Arbor, United States (Active)
Researchers
- Principal investigator: Eisenberg, Joseph N. S. — University of Michigan at Ann Arbor
- Study coordinator: Eisenberg, Joseph N. S.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.