Investigating the safety of HIV treatments during pregnancy
Methodology: Developing Reporting Criteria for Pregnancy Surveillance Cohorts and New Techniques for Supporting Target Trials
This study is looking at how HIV medications taken during pregnancy affect women and their babies in Botswana, to help ensure that future treatments are safe for both moms and their little ones.
Quick facts
| Grant type | P01 program project |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Harvard School of Public Health NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project ID | NIH-10914855 on NIH RePORTER |
What this research studies
This research focuses on the Tsepamo birth outcomes surveillance study, which collects detailed information on women living with HIV in Botswana. It aims to analyze the effects of antiretroviral (ARV) medications during pregnancy, a topic that has not been studied with high precision before. By utilizing the data from Tsepamo, the study will evaluate methodologies for reporting safety signals and improve decision-making regarding ARV use in pregnant women. The findings could provide critical insights into the safety of new HIV treatments for mothers and their infants.
Who could benefit from this research
Good fit: Ideal candidates for this research are pregnant women living with HIV, particularly those receiving antiretroviral therapy in Botswana.
Not a fit: Patients who are not pregnant or those not living with HIV may not receive any benefit from this research.
Why it matters
Potential benefit: If successful, this research could enhance the safety of HIV treatments during pregnancy, leading to better health outcomes for both mothers and infants.
How similar studies have performed: Previous studies have shown success in using surveillance data to inform treatment safety, making this approach both relevant and promising.
Where this research is happening
Boston, United States
- Harvard School of Public Health — Boston, United States (Active)
Researchers
- Principal investigator: Swanson, Sonja Alsemgeest — Harvard School of Public Health
- Study coordinator: Swanson, Sonja Alsemgeest
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.