Investigating the safety of certain sedatives during pregnancy
Safety of Benzodiazepines and Non-Benzodiazepine Sedative Hypnotics in Pregnancy
This study is looking at how safe certain sleep medications are for pregnant women, especially during the first three months, to help doctors and moms-to-be make better choices if they're dealing with anxiety or trouble sleeping.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Brigham and Women's Hospital NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project ID | NIH-11082441 on NIH RePORTER |
What this research studies
This research examines the safety of benzodiazepines and non-benzodiazepine sedative hypnotics in pregnant women, particularly focusing on their effects during the first trimester. It aims to gather comprehensive safety data to better inform the risk-benefit analysis for women experiencing anxiety disorders and insomnia during pregnancy. The study involves collaboration between mental health and obstetrical health providers to ensure informed decision-making. By analyzing the impact of these medications on fetal development, the research seeks to clarify existing conflicting evidence regarding their use.
Who could benefit from this research
Good fit: Ideal candidates for this research include pregnant women in their first trimester who are experiencing severe anxiety or insomnia.
Not a fit: Patients who are not pregnant or those who do not have anxiety disorders or insomnia may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could provide critical insights into the safe use of sedatives during pregnancy, potentially improving maternal and fetal health outcomes.
How similar studies have performed: Previous research has shown mixed results regarding the safety of sedatives during pregnancy, indicating a need for further investigation in this area.
Where this research is happening
Boston, United States
- Brigham and Women's Hospital — Boston, United States (Active)
Researchers
- Principal investigator: Huybrechts, Krista F — Brigham and Women's Hospital
- Study coordinator: Huybrechts, Krista F
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.