Investigating the role of ZEB2 in coronary artery disease risk
From Locus to Function: Role of ZEB2 in Human Risk of Coronary Artery Disease
This study is looking at how our genes might influence the risk of heart problems, specifically coronary artery disease, to help find new ways to prevent and treat it.
Quick facts
| Grant type | Career grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Stanford University NIH-funded |
| Lab location | 1 site (Stanford, United States) |
| Project ID | NIH-10888165 on NIH RePORTER |
What this research studies
This research focuses on understanding the genetic factors that contribute to coronary artery disease (CAD), which is a leading cause of death globally. By utilizing advanced techniques in genetics and epigenomics, the study aims to identify specific genes and cellular mechanisms linked to CAD risk. The principal investigator, supported by a team of experts, will employ computational and molecular methods to uncover how genetic variations affect heart health. This research could lead to new therapeutic strategies for preventing and treating CAD.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals with a family history of coronary artery disease or those identified as having a genetic predisposition to the condition.
Not a fit: Patients without any genetic risk factors for coronary artery disease may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to the development of new treatments that specifically target genetic risk factors for coronary artery disease.
How similar studies have performed: Previous research has shown success in identifying genetic risk factors for cardiovascular diseases, making this approach promising yet still innovative.
Where this research is happening
Stanford, United States
- Stanford University — Stanford, United States (Active)
Researchers
- Principal investigator: Cheng, Paul Po Sheng — Stanford University
- Study coordinator: Cheng, Paul Po Sheng
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.