Investigating the role of vaginal microbiome in menstrual pain
Vaginal Microbiome, Inflammatory Mediators, Metabolome, and Dysmenorrhea Symptom-based Phenotypes
This study is looking at how the bacteria in the vagina might influence menstrual pain, or dysmenorrhea, in women aged 14-39, to help find better ways to treat those who experience different levels of pain during their periods.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Arizona NIH-funded |
| Lab location | 1 site (Tucson, United States) |
| Project ID | NIH-11129803 on NIH RePORTER |
What this research studies
This research explores how the vaginal microbiome affects menstrual pain, known as dysmenorrhea, which varies significantly among women. By examining vaginal samples, blood samples, and questionnaire data from diverse female participants aged 14-39, the study aims to identify how different microbiome profiles correlate with varying symptoms of dysmenorrhea. The research focuses on understanding the relationship between the microbiome, inflammatory responses, and hormonal levels to personalize treatment options for menstrual pain.
Who could benefit from this research
Good fit: Ideal candidates for this research are racially diverse females aged 14-39 who experience varying levels of menstrual pain or are symptom-free.
Not a fit: Patients outside the age range of 14-39 or those who do not experience dysmenorrhea may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more personalized and effective treatments for women suffering from dysmenorrhea.
How similar studies have performed: Previous research has shown promising results in understanding the link between microbiome profiles and various health conditions, suggesting potential success for this approach.
Where this research is happening
Tucson, United States
- University of Arizona — Tucson, United States (Active)
Researchers
- Principal investigator: Chen, Chen Xiao — University of Arizona
- Study coordinator: Chen, Chen Xiao
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.