Investigating the role of TSPAN14 in heart disease
Tspan14 expression and function in cardiovascular disease
This study is looking at how differences in our genes might influence a protein called TSPAN14, which could help us understand the risk of heart disease, especially coronary artery disease, and it's for anyone interested in how genetics can affect heart health.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Ut Southwestern Medical Center NIH-funded |
| Lab location | 1 site (Dallas, United States) |
| Project ID | NIH-11134863 on NIH RePORTER |
What this research studies
This research focuses on understanding how genetic variations affect the expression of TSPAN14, a protein that may play a crucial role in coronary artery disease (CAD). By analyzing specific genetic elements and their influence on TSPAN14 in vascular cells and monocytes, the study aims to uncover how these interactions contribute to CAD risk. The researchers will utilize advanced genetic and molecular techniques to explore the functions of TSPAN14 and its potential protective effects against heart disease.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with a genetic predisposition to coronary artery disease or those who have been diagnosed with CAD.
Not a fit: Patients without any genetic risk factors for coronary artery disease may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new strategies for preventing or treating coronary artery disease by targeting TSPAN14 expression.
How similar studies have performed: Previous research has shown promising results in understanding genetic factors in coronary artery disease, suggesting that this approach could yield valuable insights.
Where this research is happening
Dallas, United States
- Ut Southwestern Medical Center — Dallas, United States (Active)
Researchers
- Principal investigator: Lee-Kim, Vivian — Ut Southwestern Medical Center
- Study coordinator: Lee-Kim, Vivian
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.