Investigating the role of TMEM55B in non-alcoholic fatty liver disease
TMEM55B as a molecular determinant of NAFLD
This study is looking at how a protein called TMEM55B affects non-alcoholic fatty liver disease (NAFLD) to help find new ways to treat this condition that can harm your liver.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California, San Francisco NIH-funded |
| Lab location | 1 site (San Francisco, United States) |
| Project ID | NIH-10922855 on NIH RePORTER |
What this research studies
This research focuses on understanding how the TMEM55B protein affects non-alcoholic fatty liver disease (NAFLD), a condition that can lead to serious liver issues like cirrhosis. The study examines the molecular mechanisms behind NAFLD by using animal models to observe the effects of TMEM55B on lipid accumulation and liver health. By manipulating TMEM55B levels, researchers aim to uncover how it influences fat mobilization and mitochondrial function in the liver. This could lead to new insights into potential therapeutic targets for treating NAFLD.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with non-alcoholic fatty liver disease or those at risk for developing it.
Not a fit: Patients with alcoholic liver disease or those without any liver conditions may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to the development of targeted therapies for non-alcoholic fatty liver disease, improving outcomes for affected patients.
How similar studies have performed: Previous research has shown promising results in understanding the molecular mechanisms of liver diseases, suggesting that this approach could yield valuable insights.
Where this research is happening
San Francisco, United States
- University of California, San Francisco — San Francisco, United States (Active)
Researchers
- Principal investigator: Medina, Marisa Wong — University of California, San Francisco
- Study coordinator: Medina, Marisa Wong
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.