Investigating the role of the TMEM230 gene in Parkinson's disease
TMEM230 and Neurodegeneration in Parkinson's Disease
This study is looking at how changes in a specific gene might play a role in developing Parkinson's disease, and it's for anyone interested in understanding the genetic factors behind this condition to help improve monitoring and treatment options.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Florida International University NIH-funded |
| Lab location | 1 site (Miami, United States) |
| Project ID | NIH-10917142 on NIH RePORTER |
What this research studies
This research focuses on understanding how mutations in the TMEM230 gene may contribute to the development of Parkinson's disease (PD), a condition characterized by the degeneration of neurons that produce dopamine. The study aims to identify genetic variants associated with late-onset PD and validate their role in the disease using both patient data and animal models. By exploring the genetic underpinnings of PD, the research seeks to uncover potential biomarkers that could help monitor disease progression and treatment effectiveness.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals with a family history of late-onset Parkinson's disease or those who have been diagnosed with the condition.
Not a fit: Patients with early-onset Parkinson's disease or those without a genetic predisposition to the condition may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding and potential new therapies for Parkinson's disease.
How similar studies have performed: Previous research has shown success in identifying genetic factors in other neurodegenerative diseases, suggesting that this approach may yield valuable insights for Parkinson's disease as well.
Where this research is happening
Miami, United States
- Florida International University — Miami, United States (Active)
Researchers
- Principal investigator: Xia, Xugang — Florida International University
- Study coordinator: Xia, Xugang
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.