Investigating the role of Th17 cells in chronic lymphocytic leukemia
Th17 generation, action and therapeutic relevance in chronic lymphocytic leukemia
This study is looking at how a special type of immune cell called Th17 cells interacts with cancer cells in chronic lymphocytic leukemia (CLL) to find new ways to help improve treatment for patients like you.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Feinstein Institute for Medical Research NIH-funded |
| Lab location | 1 site (Manhasset, United States) |
| Project ID | NIH-10735876 on NIH RePORTER |
What this research studies
This research focuses on understanding how a specific type of immune cell, known as Th17 cells, interacts with cancer cells in chronic lymphocytic leukemia (CLL). The study examines how these Th17 cells are generated and how they influence the survival and growth of CLL B cells. By analyzing the communication between these immune cells and cancer cells, the research aims to identify potential therapeutic strategies that could improve patient outcomes. Patients may be involved in providing samples to help explore these cellular interactions and their implications for treatment.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with chronic lymphocytic leukemia who are willing to participate in studies involving their immune cells.
Not a fit: Patients with other types of blood cancers or those who do not have chronic lymphocytic leukemia may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new therapies that enhance the immune response against chronic lymphocytic leukemia.
How similar studies have performed: Previous research has shown promising results in understanding the role of immune cells in cancer, suggesting that this approach could yield valuable insights.
Where this research is happening
Manhasset, United States
- Feinstein Institute for Medical Research — Manhasset, United States (Active)
Researchers
- Principal investigator: Chiorazzi, Nicholas — Feinstein Institute for Medical Research
- Study coordinator: Chiorazzi, Nicholas
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.