Investigating the role of T-lymphocytes in Parkinson's disease
Official title: Role of T-lymphocytes in Idiopathic and Genetic Parkinson's Disease
Funded at Icahn School of Medicine at Mount Sinai · NIH-10901533 · Data updated 2026-11-12
This study is looking at how certain immune cells called T-lymphocytes might affect the development and progression of Parkinson's disease, and it involves patients providing blood samples to help us understand these immune changes better.
Quick facts
| Grant type | Fellowship grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Icahn School of Medicine at Mount Sinai NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project start | July 1, 2024 |
| Project end | August 31, 2026 |
| Funding year | 2024 |
| Award (this year) | $47,374 |
| NIH project number | 1F31NS134319-01A1 |
| Project ID | NIH-10901533 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for participation include individuals diagnosed with Parkinson's disease, particularly those in various stages of the condition.
✕Less likely to help
Patients with other neurodegenerative diseases or those without a Parkinson's disease diagnosis may not benefit from this research.
What this research studies
This research focuses on understanding how T-lymphocytes, a type of immune cell, contribute to the development and progression of Parkinson's disease (PD). By analyzing blood samples and brain tissue, the study aims to identify specific immune alterations associated with PD and how these changes may influence neurodegeneration. The research will utilize advanced techniques to explore the interactions between T-cells and other immune cells, particularly in different stages of the disease. Patients may be involved in providing blood samples to help clarify the role of these immune cells in PD.
Why it matters
Potential benefit: If successful, this research could lead to new insights into the immune mechanisms of Parkinson's disease, potentially paving the way for novel therapeutic strategies.
How similar studies have gone: Previous research has indicated that immune system involvement in neurodegenerative diseases can lead to significant findings, suggesting that this approach may yield valuable insights.
Where this research is happening
-
Icahn School of Medicine at Mount Sinai
New York, United States Active
Researchers
- Principal investigator: Rosen, Mikaela — Icahn School of Medicine at Mount Sinai
- Study coordinator: Rosen, Mikaela
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.