Investigating the role of sugars and carbohydrates in human tissues
Official title: Mass Spectrometric Tissue Imaging of Sugars, Glycans, and Glycoconjugates
Funded at Battelle Pacific Northwest Laboratories · NIH-11009264 · Data updated 2026-11-12
This study is looking at how sugars in our cells change and how these changes might be affected by our environment, which could help us understand different health conditions better.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Battelle Pacific Northwest Laboratories NIH-funded |
| Lab location | 1 site (Richland, United States) |
| Project start | April 10, 2025 |
| Project end | March 31, 2030 |
| Funding year | 2025 |
| Award (this year) | $417,400 |
| NIH project number | 1R35GM156251-01 |
| Project ID | NIH-11009264 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals with conditions that may be influenced by glycan structures, such as metabolic disorders or certain cancers.
✕Less likely to help
Patients without any known metabolic or glycan-related disorders may not benefit from this research.
What this research studies
This research focuses on understanding the glycome, which encompasses all carbohydrates associated with cells, including those linked to proteins and lipids. By utilizing advanced mass spectrometry imaging techniques, the study aims to identify and visualize changes in carbohydrate structures at the cellular level, which can be crucial for understanding various biological processes and diseases. The research will explore how environmental factors influence glycan production and how these changes can be linked to health conditions. This innovative approach seeks to provide insights that traditional methods have not been able to achieve.
Why it matters
Potential benefit: If successful, this research could lead to better diagnostic tools and therapeutic strategies for diseases linked to glycan abnormalities.
How similar studies have gone: While mass spectrometry imaging has been successful in other areas, its application in glycome imaging is still emerging and represents a novel approach.
Where this research is happening
-
Battelle Pacific Northwest Laboratories
Richland, United States Active
Researchers
- Principal investigator: Velickovic, Dusan — Battelle Pacific Northwest Laboratories
- Study coordinator: Velickovic, Dusan
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.