Investigating the role of stem cells in endometriosis
Targeting the endometrial stem cell niche inendometriosis
This study is looking at how certain stem cells in the uterus might play a role in endometriosis, a condition that causes pain and can affect fertility, to find new ways to help women who are dealing with this issue.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Baylor College of Medicine NIH-funded |
| Lab location | 1 site (Houston, United States) |
| Project ID | NIH-11097368 on NIH RePORTER |
What this research studies
This research focuses on understanding how endometrial stem cells contribute to the development of endometriosis, a condition where tissue similar to the lining of the uterus grows outside of it, causing pain and infertility. The study utilizes advanced techniques such as endometrial organoid cultures and mouse models to explore the signaling pathways involved in stem cell behavior and their impact on ectopic tissue growth. By examining the roles of specific proteins and enzymes, the research aims to uncover potential therapeutic targets for improving treatment options for affected women.
Who could benefit from this research
Good fit: Ideal candidates for this research are women aged 21 and older who have been diagnosed with endometriosis.
Not a fit: Patients who do not have endometriosis or are under 21 years old may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new treatments that alleviate pain and improve fertility for women suffering from endometriosis.
How similar studies have performed: Previous research has shown promising results in understanding stem cell roles in other conditions, suggesting potential for success in this novel approach to endometriosis.
Where this research is happening
Houston, United States
- Baylor College of Medicine — Houston, United States (Active)
Researchers
- Principal investigator: Monsivais, Diana — Baylor College of Medicine
- Study coordinator: Monsivais, Diana
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.