Investigating the role of specific proteins in pancreatic cancer progression
Targeting aberrant enhancer landscapes in pancreatic cancer
This study is looking at how specific proteins affect the growth of pancreatic cancer, with the hope of finding new ways to treat it that could help patients like you.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Cold Spring Harbor Laboratory NIH-funded |
| Lab location | 1 site (Cold Spring Harbor, United States) |
| Project ID | NIH-10978483 on NIH RePORTER |
What this research studies
This research focuses on understanding how certain proteins influence the development and progression of pancreatic ductal adenocarcinoma (PDAC). By utilizing advanced techniques like epigenomics and CRISPR genetic screening, the team aims to uncover the molecular mechanisms that drive changes in cell identity during cancer progression. The research specifically targets the role of transcription factors that are involved in maintaining cancerous traits, with the goal of identifying potential therapeutic targets. Patients may benefit from insights that could lead to new treatment strategies for this aggressive cancer.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with pancreatic ductal adenocarcinoma, particularly those experiencing disease progression or treatment resistance.
Not a fit: Patients with other types of cancer or those without pancreatic ductal adenocarcinoma may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new targeted therapies for pancreatic cancer, improving treatment options and outcomes for patients.
How similar studies have performed: Previous research has shown promise in targeting transcription factors in cancer, suggesting that this approach could yield significant advancements in treatment.
Where this research is happening
Cold Spring Harbor, United States
- Cold Spring Harbor Laboratory — Cold Spring Harbor, United States (Active)
Researchers
- Principal investigator: Vakoc, Christopher — Cold Spring Harbor Laboratory
- Study coordinator: Vakoc, Christopher
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.