Investigating the role of specific immune cells in high blood pressure
Official title: The Role of CCR10 and CCR10+ Tregs in Hypertension
Funded at Vanderbilt University · NIH-10998077 · Data updated 2026-11-12
This study is looking at how a special type of immune cell might affect high blood pressure, and it's for people with hypertension who want to help find new treatment options based on how the immune system works.
Quick facts
| Grant type | Fellowship grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Vanderbilt University NIH-funded |
| Lab location | 1 site (Nashville, UNITED STATES) |
| Project start | December 1, 2024 |
| Project end | November 30, 2027 |
| Funding year | 2024 |
| Award (this year) | $34,370 |
| NIH project number | 1F31HL176154-01 |
| Project ID | NIH-10998077 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include individuals diagnosed with hypertension, particularly those aged 21 and older.
✕Less likely to help
Patients with hypertension who do not have a significant immune component to their condition may not benefit from this research.
What this research studies
This research focuses on understanding how certain immune cells, particularly a subset known as CCR10+ regulatory T cells, influence high blood pressure (hypertension). By examining blood samples from individuals with hypertension and healthy controls, the study aims to identify differences in immune cell populations. The researchers will use advanced techniques to analyze these cells and explore their potential role in regulating blood pressure and associated health risks. Patients may benefit from insights that could lead to new treatments for hypertension based on immune system interactions.
Why it matters
Potential benefit: If successful, this research could lead to innovative therapies that better manage or even prevent hypertension by targeting immune cell functions.
How similar studies have gone: While the role of immune cells in hypertension is an emerging field, this specific investigation into CCR10+ Tregs is novel and has not been extensively tested in prior studies.
Where this research is happening
-
Vanderbilt University
Nashville, United States Active
Researchers
- Principal investigator: Nguyen, Bianca Alexandra — Vanderbilt University
- Study coordinator: Nguyen, Bianca Alexandra
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.