Investigating the role of specific immune cells in heart attacks
Role of group 2 innate lymphoid cells in myocardial infarction
This study is looking at how certain immune cells in your body, called ILC2 and eosinophils, affect heart health after a heart attack, with the goal of finding better ways to help people recover from such events.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Brigham and Women's Hospital NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project ID | NIH-10991700 on NIH RePORTER |
What this research studies
This research focuses on understanding how group 2 innate lymphoid cells (ILC2) and eosinophils contribute to heart disease, particularly after a myocardial infarction (heart attack). It explores the relationship between these immune cells and inflammation, which is known to play a significant role in cardiovascular disease. By studying the effects of ILC2 on heart function and recovery, the research aims to uncover new insights that could lead to improved treatments for patients who have suffered from heart attacks.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals who have experienced a myocardial infarction or are at high risk for heart disease.
Not a fit: Patients with stable heart conditions who have not experienced a myocardial infarction may not receive direct benefits from this research.
Why it matters
Potential benefit: If successful, this research could lead to new therapeutic strategies that enhance heart recovery and reduce complications after a heart attack.
How similar studies have performed: Previous studies have shown promising results regarding the role of immune cells in cardiovascular health, suggesting that this research could build on established findings.
Where this research is happening
Boston, United States
- Brigham and Women's Hospital — Boston, United States (Active)
Researchers
- Principal investigator: Libby, Peter — Brigham and Women's Hospital
- Study coordinator: Libby, Peter
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.