Investigating the role of sodium in skin health and atopic dermatitis
Official title: Sodium in the Skin and Atopic Dermatitis: The SIS-AD Study
Funded at University of California, San Francisco · NIH-10933427 · Data updated 2026-11-12
This study is looking at how too much salt in our diet might affect the skin and make atopic dermatitis worse, and it aims to find out if cutting back on salt can help improve symptoms for people dealing with this skin condition.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California, San Francisco NIH-funded |
| Lab location | 1 site (San Francisco, United States) |
| Project start | September 22, 2023 |
| Project end | August 31, 2028 |
| Funding year | 2024 |
| Award (this year) | $688,519 |
| NIH project number | 5R01AR082831-02 |
| Project ID | NIH-10933427 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include individuals suffering from atopic dermatitis, particularly those with high sodium intake or poor skin barrier function.
✕Less likely to help
Patients who do not have atopic dermatitis or those whose condition is not influenced by dietary factors may not benefit from this research.
What this research studies
This research explores how excess dietary sodium affects the skin and contributes to atopic dermatitis, a common and burdensome skin condition. The study aims to understand the relationship between sodium levels in the skin and the severity of atopic dermatitis symptoms. By examining dietary sodium intake and skin barrier function, researchers hope to identify modifiable factors that could improve patient outcomes. The ultimate goal is to determine if reducing sodium intake can alleviate symptoms of atopic dermatitis.
Why it matters
Potential benefit: If successful, this research could lead to new dietary recommendations that improve the management of atopic dermatitis for patients.
How similar studies have gone: Previous research has indicated that dietary factors can influence skin conditions, suggesting that this approach may yield valuable insights.
Where this research is happening
-
University of California, San Francisco
San Francisco, United States Active
Researchers
- Principal investigator: Abuabara, Katrina Elaine — University of California, San Francisco
- Study coordinator: Abuabara, Katrina Elaine
Related research
Other NIH-funded projects on the same topics.
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Stopping Atopic Dermatitis and Allergy: Preventing Food Allergy by Protecting the Skin
A large study in infants at high risk for allergies tests whether using a skin barrier cream together with early, proactive skin care can prevent peanut allergy and other food allergies.
-
SEAL Study: Preventing peanut allergy by protecting baby skin
This trial tests whether using a skin-emollient and proactive skin steroids early in life can prevent peanut allergy in high-risk infants.
-
SEAL Study: Prevent allergy by protecting the baby’s skin
A very young group of high-risk babies will try a early skin-care plan to reduce eczema and prevent peanut allergy.
-
Understanding how skin fungi affect atopic dermatitis in adults
A study will look at how the skin's fungal community influences atopic dermatitis in adults and whether this understanding could lead to new treatments.
-
Preventing eczema-related allergies by strengthening infants' skin barrier
This project will see if using a trilipid skin cream plus proactive mild topical steroids in infants with early dry skin or eczema lowers their chances of developing food allergies.
-
Personalized predictions for how atopic dermatitis may progress in kids and teens
A patient-friendly plan to forecast how early-onset eczema might evolve in children and young people using simple health clues and data from diverse settings.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.