Investigating the role of sodium in skin health and atopic dermatitis

Sodium in the Skin and Atopic Dermatitis: The SIS-AD Study

NIH-funded research University of California, San Francisco · NIH-10933427

This study is looking at how too much salt in our diet might affect the skin and make atopic dermatitis worse, and it aims to find out if cutting back on salt can help improve symptoms for people dealing with this skin condition.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of California, San Francisco NIH-funded
Lab location1 site (San Francisco, United States)
Project IDNIH-10933427 on NIH RePORTER

What this research studies

This research explores how excess dietary sodium affects the skin and contributes to atopic dermatitis, a common and burdensome skin condition. The study aims to understand the relationship between sodium levels in the skin and the severity of atopic dermatitis symptoms. By examining dietary sodium intake and skin barrier function, researchers hope to identify modifiable factors that could improve patient outcomes. The ultimate goal is to determine if reducing sodium intake can alleviate symptoms of atopic dermatitis.

Who could benefit from this research

Good fit: Ideal candidates for this research include individuals suffering from atopic dermatitis, particularly those with high sodium intake or poor skin barrier function.

Not a fit: Patients who do not have atopic dermatitis or those whose condition is not influenced by dietary factors may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to new dietary recommendations that improve the management of atopic dermatitis for patients.

How similar studies have performed: Previous research has indicated that dietary factors can influence skin conditions, suggesting that this approach may yield valuable insights.

Where this research is happening

San Francisco, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-10 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.