Investigating the role of S100 proteins in diabetic eye disease
Role of S100 proteins in Diabetic Retinopathy
This study is looking at how certain proteins in the eye might play a role in worsening diabetic retinopathy, a common eye problem for people with diabetes, to find new ways to help manage the condition better.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Medical College of Wisconsin NIH-funded |
| Lab location | 1 site (Milwaukee, United States) |
| Project ID | NIH-10666595 on NIH RePORTER |
What this research studies
This research focuses on diabetic retinopathy, a serious eye condition affecting many people with diabetes. It aims to understand how S100 proteins, which are involved in various cellular functions, contribute to the disease's progression. By studying these proteins in the context of diabetic stress, the researchers hope to identify new treatment targets that could lead to better management of diabetic retinopathy. The approach includes examining changes in the retina and how these proteins interact with retinal cells under diabetic conditions.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with diabetes who are at risk of developing diabetic retinopathy.
Not a fit: Patients without diabetes or those who have advanced stages of diabetic retinopathy may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new treatments for diabetic retinopathy that are more effective and less invasive than current options.
How similar studies have performed: Other research has shown promise in targeting molecular pathways in diabetic retinopathy, suggesting that this approach could yield valuable insights.
Where this research is happening
Milwaukee, United States
- Medical College of Wisconsin — Milwaukee, United States (Active)
Researchers
- Principal investigator: Chaurasia, Shyam Sunder — Medical College of Wisconsin
- Study coordinator: Chaurasia, Shyam Sunder
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.