Investigating the role of Rab10 in Alzheimer's disease
Role of Rab10 in Alzheimer's disease
This study is looking at how a protein called Rab10 affects brain inflammation and damage in Alzheimer's disease, using mice to find new ways to help treat the condition.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Alabama at Birmingham NIH-funded |
| Lab location | 1 site (Birmingham, United States) |
| Project ID | NIH-11088897 on NIH RePORTER |
What this research studies
This research focuses on understanding how Rab10, a key regulator of cellular processes, influences neuroinflammation and neurodegeneration in Alzheimer's disease. The approach involves using mouse models to explore the molecular mechanisms behind endocytic trafficking pathways and their impact on disease progression. The research aims to identify potential therapeutic targets that could mitigate the effects of Alzheimer's. By combining experimental studies with formal training, the project seeks to advance knowledge in the field of neurobiology.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with Alzheimer's disease or those at risk of developing it.
Not a fit: Patients with other forms of dementia unrelated to Alzheimer's may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new therapeutic strategies for treating Alzheimer's disease.
How similar studies have performed: Previous research has shown promise in targeting molecular mechanisms related to neuroinflammation in Alzheimer's, suggesting potential for success in this area.
Where this research is happening
Birmingham, United States
- University of Alabama at Birmingham — Birmingham, United States (Active)
Researchers
- Principal investigator: Liu, Zhiyong — University of Alabama at Birmingham
- Study coordinator: Liu, Zhiyong
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.