Investigating the role of placental proteins in preventing premature birth.
Official title: Placental Proteins and Prematurity
Funded at University of Colorado Denver · NIH-11020649 · Data updated 2026-11-12
This study is looking at how certain proteins from the placenta affect baby development and might cause early births, with the goal of finding ways to help prevent preterm labor and improve health for babies born too soon.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Colorado Denver NIH-funded |
| Lab location | 1 site (Aurora, UNITED STATES) |
| Project start | December 1, 2024 |
| Project end | November 30, 2029 |
| Funding year | 2025 |
| Award (this year) | $641,883 |
| NIH project number | 1R01HD116753-01 |
| Project ID | NIH-11020649 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are pregnant individuals at risk of preterm labor or those who have experienced preterm births in the past.
✕Less likely to help
Patients who are not pregnant or those who have no history of preterm labor may not benefit from this research.
What this research studies
This research focuses on understanding how proteins secreted by the placenta influence fetal development and may contribute to preterm birth. By studying these proteins, the researchers aim to uncover mechanisms that lead to premature labor and identify potential interventions. The approach includes analyzing the proteins found in the fetal circulation before 32 weeks of gestation and their roles in critical processes such as organ development and neurogenesis. This could lead to new strategies for preventing preterm birth and improving outcomes for infants born prematurely.
Why it matters
Potential benefit: If successful, this research could lead to new treatments that prevent preterm birth and improve health outcomes for infants.
How similar studies have gone: Previous animal studies have shown promising results regarding the role of placental factors in fetal development, indicating potential for success in this area.
Where this research is happening
-
University of Colorado Denver
Aurora, United States Active
Researchers
- Principal investigator: Jansson, Thomas — University of Colorado Denver
- Study coordinator: Jansson, Thomas
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.