Investigating the role of oral fungi in pancreatic cancer risk
The Oral Mycobiome and Risk of Pancreatic Cancer
This study is looking at how certain fungi in your mouth might be linked to pancreatic cancer, and it involves collecting samples from people to see if these fungi could increase cancer risk, with the hope of finding ways to prevent the disease.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | New York University School of Medicine NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project ID | NIH-10894858 on NIH RePORTER |
What this research studies
This research explores how oral fungi may contribute to the development of pancreatic cancer by affecting the immune environment of the pancreas. The study involves collecting oral samples from participants to analyze the fungal microbiome and its potential link to cancer risk. Researchers will conduct a nested case-control study to assess whether specific oral fungi are associated with an increased risk of pancreatic cancer. The ultimate goal is to identify and manage these fungi to help prevent the disease.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals with a history of oral health issues or those at high risk for pancreatic cancer.
Not a fit: Patients who do not have any oral health concerns or those who are not at risk for pancreatic cancer may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new preventive strategies for pancreatic cancer by targeting oral fungal microbiota.
How similar studies have performed: Other research has shown promising results in understanding the role of microbiomes in cancer, suggesting that this approach could yield valuable insights.
Where this research is happening
New York, United States
- New York University School of Medicine — New York, United States (Active)
Researchers
- Principal investigator: Ahn, Jiyoung — New York University School of Medicine
- Study coordinator: Ahn, Jiyoung
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.