Investigating the role of neurotensin in ovulation
Neurotensin: A Novel Mediator of Ovulation
This study is looking at how a tiny protein called neurotensin affects ovulation in women, with the hope of finding new ways to help women who have trouble getting pregnant due to ovulation issues.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Kentucky NIH-funded |
| Lab location | 1 site (Lexington, United States) |
| Project ID | NIH-10657389 on NIH RePORTER |
What this research studies
This research explores how neurotensin, a small neuropeptide, influences the ovulation process in women. By examining the changes in neurotensin levels in ovarian cells during the ovulatory phase, the study aims to understand its role as a key mediator in the release of oocytes. The research utilizes both in vitro and in vivo models, including rodent and monkey studies, to assess how neurotensin affects ovulation and to identify potential therapeutic targets for improving fertility. The findings could lead to new insights into treating female infertility linked to ovulatory defects.
Who could benefit from this research
Good fit: Ideal candidates for this research are women experiencing infertility due to ovulatory dysfunction.
Not a fit: Patients who do not have ovulatory issues or those with infertility due to other causes may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could provide new strategies for treating female infertility by targeting neurotensin pathways.
How similar studies have performed: While the role of neurotensin in ovulation is not widely studied, preliminary data suggests it may be a promising area for further exploration.
Where this research is happening
Lexington, United States
- University of Kentucky — Lexington, United States (Active)
Researchers
- Principal investigator: Curry, Thomas E — University of Kentucky
- Study coordinator: Curry, Thomas E
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.