Investigating the role of metabolites in menopause-related urogenital health across different races and ethnicities.
Official title: A multi-omic and integrative longitudinal evaluation of the role of lipid, antioxidant, and osmoprotectant metabolites in the genitourinary syndrome of menopause by race and ethnicity.
Funded at Montana State University - Bozeman · NIH-10885940 · Data updated 2026-11-12
This study is looking at how certain substances in the body affect the genitourinary syndrome of menopause (GSM) and overall vaginal health in postmenopausal women, especially those from different racial and ethnic backgrounds, to help improve their well-being during this stage of life.
Quick facts
| Grant type | Career grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Montana State University - Bozeman NIH-funded |
| Lab location | 1 site (Bozeman, United States) |
| Project start | July 15, 2023 |
| Project end | June 30, 2025 |
| Funding year | 2024 |
| Award (this year) | $138,029 |
| NIH project number | 5K99AG081495-02 |
| Project ID | NIH-10885940 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are postmenopausal women, especially those from diverse racial and ethnic backgrounds.
✕Less likely to help
Patients who are not postmenopausal or who do not have symptoms related to the genitourinary syndrome of menopause may not benefit from this research.
What this research studies
This research focuses on the genitourinary syndrome of menopause (GSM), a condition that affects many postmenopausal women, particularly those from racial and ethnic minorities. It aims to understand how various metabolites, including lipids and antioxidants, influence GSM and overall urogenital health. By analyzing a large cohort of women, the study will explore the relationship between aging, hormonal changes, and the vaginal microbiota, which plays a crucial role in sexual health. The research will utilize a multi-omic approach to gather comprehensive data on these interactions over time.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding and management of menopause-related urogenital health issues, particularly for underrepresented populations.
How similar studies have gone: While the specific multi-omic approach may be novel, previous research has shown success in understanding the role of metabolites in various health conditions, indicating potential for impactful findings.
Where this research is happening
-
Montana State University - Bozeman
Bozeman, United States Active
Researchers
- Principal investigator: Borgogna, Joanna-Lynn C — Montana State University - Bozeman
- Study coordinator: Borgogna, Joanna-Lynn C
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.