Investigating the role of long non-coding RNAs in glioblastoma
Systematic dissection of function and mechanism of long non-coding RNAs in glioblastoma
This study is looking at a type of brain tumor called glioblastoma to find out how certain molecules in our genes might help the tumor grow, with the hope that this could lead to new treatments for patients like you.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Tx Md Anderson Can Ctr NIH-funded |
| Lab location | 1 site (Houston, United States) |
| Project ID | NIH-11042795 on NIH RePORTER |
What this research studies
This research focuses on glioblastoma, a highly aggressive brain tumor with limited treatment options. It aims to understand the function and mechanisms of long non-coding RNAs (lncRNAs) in glioblastoma development and progression. By employing advanced techniques like CRISPR interference, the study will identify specific lncRNAs that contribute to tumor growth and could serve as potential therapeutic targets. Patients may benefit from insights that could lead to new treatment strategies based on these findings.
Who could benefit from this research
Good fit: Ideal candidates for this research are adults diagnosed with glioblastoma.
Not a fit: Patients with other types of brain tumors or those who do not have glioblastoma may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new therapeutic strategies that improve outcomes for glioblastoma patients.
How similar studies have performed: Other research has shown promise in targeting lncRNAs for cancer treatment, indicating potential success for this approach.
Where this research is happening
Houston, United States
- University of Tx Md Anderson Can Ctr — Houston, United States (Active)
Researchers
- Principal investigator: Chen, Yiwen — University of Tx Md Anderson Can Ctr
- Study coordinator: Chen, Yiwen
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.