Investigating the role of immune cells in Parkinson's disease
The Role of Myeloid Cells in Parkinson's Disease
This study is looking at how certain immune cells might play a role in Parkinson's disease by examining blood samples from people in the early stages of the condition, with the hope of finding new ways to treat it and better understand how it works.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Icahn School of Medicine at Mount Sinai NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project ID | NIH-11099670 on NIH RePORTER |
What this research studies
This research focuses on understanding how myeloid cells, a type of immune cell, contribute to Parkinson's disease (PD). By analyzing genetic variants and their effects on gene expression in these cells, the study aims to uncover the molecular pathways involved in PD. Researchers will collect and analyze blood samples from patients with early-stage PD to create detailed profiles of gene activity and protein expression. This approach may help identify potential targets for new treatments and improve our understanding of the disease.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with early-stage Parkinson's disease who are not currently on medication.
Not a fit: Patients with advanced Parkinson's disease or those who are already receiving treatment may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new therapeutic strategies for Parkinson's disease, potentially improving patient outcomes.
How similar studies have performed: Previous research has shown success in using genetic and transcriptomic approaches to understand other neurodegenerative diseases, suggesting that this methodology could be effective for Parkinson's disease as well.
Where this research is happening
New York, United States
- Icahn School of Medicine at Mount Sinai — New York, United States (Active)
Researchers
- Principal investigator: Raj, Towfique — Icahn School of Medicine at Mount Sinai
- Study coordinator: Raj, Towfique
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.