Investigating the role of gut health in treating ALS
Microbiome and intestinal barrier in ALS therapy
This study is looking at how the health of your gut might influence the progression of ALS, especially in veterans, to find new ways to improve gut health and help with ALS symptoms.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Jesse Brown VA Medical Center NIH-funded |
| Lab location | 1 site (Chicago, United States) |
| Project ID | NIH-11046270 on NIH RePORTER |
What this research studies
This research explores how the gut microbiome and intestinal function affect patients with Amyotrophic Lateral Sclerosis (ALS). It aims to understand the connection between gut health and the progression of ALS, particularly in veterans who are at higher risk for the disease. By examining the gut-neuron-microbial axis, the study seeks to identify potential treatments that could restore gut health and improve neurological function. The research utilizes both animal models and human samples to investigate the effects of gut microbiome alterations on ALS symptoms.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with Amyotrophic Lateral Sclerosis, particularly veterans.
Not a fit: Patients with other neurological disorders unrelated to ALS may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new therapeutic strategies that improve the quality of life and slow the progression of ALS.
How similar studies have performed: Previous research has shown promising results in understanding the microbiome's role in neurological diseases, suggesting potential for success in this novel approach.
Where this research is happening
Chicago, United States
- Jesse Brown VA Medical Center — Chicago, United States (Active)
Researchers
- Principal investigator: Sun, Jun — Jesse Brown VA Medical Center
- Study coordinator: Sun, Jun
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.