Investigating the role of Gstt1 in pancreatic cancer metastasis
Role of Gstt1 in metastatic maintenance and self-renewal in PDA
This study is looking at how a specific gene affects the growth of advanced pancreatic cancer cells, with the hope of finding new ways to treat patients facing this tough disease.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Maryland Baltimore NIH-funded |
| Lab location | 1 site (Baltimore, United States) |
| Project ID | NIH-10925336 on NIH RePORTER |
What this research studies
This research focuses on understanding how the Gstt1 gene influences the maintenance and self-renewal of metastatic pancreatic ductal adenocarcinoma (PDA) cells. By studying both primary and metastatic tumor tissues, the researchers aim to identify vulnerabilities in metastatic lesions that could lead to new treatment strategies. The approach includes advanced techniques like RNA sequencing and functional assays to uncover the unique requirements for the growth of metastatic cancer cells. This could provide insights into potential therapeutic targets for patients with advanced cancer.
Who could benefit from this research
Good fit: Ideal candidates for this research are patients diagnosed with metastatic pancreatic ductal adenocarcinoma.
Not a fit: Patients with early-stage pancreatic cancer or those without metastatic disease may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new treatment options for patients suffering from metastatic pancreatic cancer.
How similar studies have performed: Other research has shown promise in targeting metastatic cancer mechanisms, suggesting that this approach could yield significant insights.
Where this research is happening
Baltimore, United States
- University of Maryland Baltimore — Baltimore, United States (Active)
Researchers
- Principal investigator: Ferrer, Christina — University of Maryland Baltimore
- Study coordinator: Ferrer, Christina
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.